Learning about micro services with python, I found a great tool named nameko . https://www.nameko.io/ Nameko is a Python framework to build microservices that doesn't care in concrete technologies you will use within your project. To allow that microservices to work with a database, you can install into your project a wide variety of third parties, like SQLAlchemy (just like any other). To have an easy way to communicate with the database and keep track of the changes made to the models, I chose Django: I'm just learning about microservices and I want to keep focused on that. Easy to use, Django is a reliable web framework, have a powerful and well known ORM. Also using Django we will have many of the different functionalities that this framework provide. To make all this magic to work together, I developed a python package that allow you to use Django as a Nameko injected dependency: https://pypi.org/project/django-nameko-standalone/ You can found the source